RT Journal Article
SR Electronic
T1 Erythrocytosis and hypopnea syndrome sleep apnea. Effect of CPAP
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2261
VO 44
IS Suppl 58
A1 Carolina Jurkojc
A1 Paola Arrieta
A1 Eva Mañas
A1 Carolina Gotera
A1 Rosa Mirambeaux
A1 Deisy Barrios
A1 Patricia Lazo
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P2261.abstract
AB Introduction: Polycythemia is a finding in patients with obstructive sleep apnoea hypopnoea syndrome (SAHS). If the hematocrit (HCT) increase was due to intermittent nocturnal hypoxia, it would be interesting to analyze whether CPAP treatment produces a decrease in HCT, translating a correction of hypoxic events.Material and Methods : 20 patients referred from the hematology unit for respiratory sleep disorders evaluated during 2012-2013 . They did study with cardiorespiratory polygraphy. Those patients diagnosed with SAHS were treated with CPAP. After 6 months of treatment, underwent a blood test . Hemoglobin (HB) levels and HCT were compared before and after CPAP , using the Wilcoxon test for nonparametric variables.Results : All patients were male. The mean age was 64.5 (SD 13.6). 85% (17 ) patients were diagnosed with SAHS. The mean respiratory disturbance index ( RDI ) resulted 32.7 (SD 25.6 ) . The minimum was 0.7 and the maximum 81 . Half of the patients showed severe SAHS. The nocturnal oximetry profile presented with an average of 41 % T90 % (SD 35 ) and a middle desaturation index 34.4 / h ( SD 25 ) . A predominance of obstructive SAHS was observed. When comparing HB and HCT before and after treatment with CPAP , a reduction of both parameters was observed , with a significant differenceView this table:.Conclusion: Patients with SAHS and poliglobulia show an improvement in red cell parameters after treatment with CPAP. Studies with larger series are needed to verify these results.