%0 Journal Article %A Louis-Marie Galerneau %A Atallah Ihab %A Briault Amandine %A Pra Yves %A Jankowski Adrien %A Vincent Caroline %A Ferretti Gilbert %A Aniwidyaningsih Wahju %A Reyt Emile %A Righini Christian %A Pison Christophe %T Survival after covered Y-shaped stents in malignant lesions of the carina %D 2014 %J European Respiratory Journal %P P712 %V 44 %N Suppl 58 %X We evaluated the effects of Y-stenting in malignant carina lesions on respiratory failure treatments and survival. Moreover, we post-hoc analysed which patients benefited the most of these palliative care. Thiry-two consecutive patients, 61.0±8.4 yrs. old, 26 men were treated with Y-stent (Microtec, China), inserted between II-09 to X-13, under general anaesthesia with rigid bronchoscopy under brilliancyamplifier. Lung cancers were 62.5 %, oesophageal cancers 37.5%, stage I 7%, II 10 %, III 50% and IV 33%. Median follow-up was 106 days (m-M: 3-673). No deaths were related to the procedure. Survival according to Kaplan Meier analysis were 64%, 45%, 34% and 8% at 1, 2, 3 month and 1 year respectively; median survival was 49 days. Ventilation and oxygen therapy in pre procedure were used in 3 and 10 respectively and 1 and 10 after stent insertion, p: 0.12 for oxygen therapy. A multivariate Cox related to survival showed no effects of age, gender, BMI or lung versus oesophageal cancers. Subjective improvement in symptoms, the main goal of these procedures has not been adequately measured which was the main limitation of our series. As compared to previous series, our median survival seemed to be shorter, and as others we were unable to unravel prognosis factors suggesting that carina localisation has a very poor prognosis per se independently of co-variables as stage, BMI, age and gender. We were unable to find any prognostic factors on survival, resulting in persistent issue to select patients that will benefit the most. An assessment of quality of life is mandatory to support these palliative procedures and to better anticipate survival benefits probably in intermediate performance group. %U