TY - JOUR T1 - Clinical spectrum of adult bronchiolitis – An eleven years retrospective analysis JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P757 AU - Paulo Matos AU - Daniela Madama AU - Maria João Matos AU - Lina Carvalho Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P757.abstract N2 - Introduction: Bronchiolitis are a heterogeneous group of inflammatory diseases of the small airways, primary or secondary to other systemic diseases, but mostly with viral cause or associated with tobacco exposure. Regarding the difficulty of a specific diagnosis and the lack of literature in the subject, it is important to characterize this pathology.Objective: To describe epidemiologic, functional and radiologic characteristics in patients with histologic diagnosis of bronchiolitis.Materials and methods: Retrospective analysis through hospitalar data consultation of patients with histological diagnosis of bronchiolitis during the 2000-2011 period.Results: 193 histological diagnoses of bronchiolitis were confirmed. Mean age was 48.72 (±17.16) with male predominance (69.4%). Respiratory co-morbiditie was the most frequent (28%). Histologicaly there was prevalence for Respiratory bronchiolitis (RB) (53.9%), Obliterative bronchiolitis (OB) (16.1%) and Constrictive bronchiolitis (CB) (11.4%). Chronic symptoms were present all histological types, less evident in RB (acute symptoms in 43.9%). Smooking was most related to RB (80.7%). The main radiologic finding in RB was pneumothorax (38.5%) and ground glass opacities in OB (32.1%) and CB (36.6%). Pulmonary nodules or masses were found in 22.3%, mainly associated with Folicular bronchiolitis (50%). Spirometry was normal in 69% and obstructive in 23.5% of patients.Conclusions: The majority of diagnosis corresponded to secondary bronchiolitis associated with respiratory pathology, mainly due to tobacco abuse. Our study shows the importance to correlate the radiological and clinical features in order to obtain a definitive diagnosis. ER -