RT Journal Article
SR Electronic
T1 The evaluation of pulmonary function of children with bronchiolitis obliterans by spirometry and impulse oscillometry methods
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4532
VO 44
IS Suppl 58
A1 Zeynep Seda Uyan
A1 Erkan Çakir
A1 Yasemin Gökdemir
A1 Levent Midyat
A1 Ersin Öztürk
A1 Velat Sen
A1 Ahmet Hakan Gedik
A1 Ela Erdem
A1 Bülent Karadag
A1 Fazilet Karakç
A1 Refika Ersu
YR 2014
UL http://erj.ersjournals.com/content/44/Suppl_58/P4532.abstract
AB Bronchiolitis obliterans (BO) is characterized by persistent symptoms of obstructive lung disease following acute bronchial injury. Our aim was to evaluate the pulmonary function of children with BO by spirometry and impulse oscillometry (IOS) methods. Forty-one postinfectious BO patients (71% male) with a mean age of 106±60 months, followed for a median period of 29 (IQR: 7.5-105.5) months in three different centres were enrolled. Mean age at diagnosis was 41±32 months. Their median z-score of weight was -0,49 (IQR:-2.39-0.67) while median z-score of height was -0,82 (IQR: -1.80-0.35). Mean FEV1 value was 48.8±14.2%, FVC was 56.8±11.9% in 26 patients who could perform spirometry. When the IOS results of BO patients were compared with their spirometry results, percent of resistance values at 5,10,15 and 20 hz (R5, R10, R15 and R20) (p=0.00, 0.00, 0.00 ve 0.01, respectively) and resonance frequency (p=0.00) correlated negatively while reactance values at 5,10,15 and 20 hz (X5, X10, X15 and X20) (p=0.00, 0.01, 0.01, 0.00, respectively) correlated positively with FEV1 results. In conclusion; pulmonary function of children with BO who cannot perform spirometry can be evaluated by IOS method in which only minimal cooperation is needed.