TY - JOUR T1 - The evaluation of pulmonary function of children with bronchiolitis obliterans by spirometry and impulse oscillometry methods JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P4532 AU - Zeynep Seda Uyan AU - Erkan Çakir AU - Yasemin Gökdemir AU - Levent Midyat AU - Ersin Öztürk AU - Velat Sen AU - Ahmet Hakan Gedik AU - Ela Erdem AU - Bülent Karadag AU - Fazilet Karakç AU - Refika Ersu Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P4532.abstract N2 - Bronchiolitis obliterans (BO) is characterized by persistent symptoms of obstructive lung disease following acute bronchial injury. Our aim was to evaluate the pulmonary function of children with BO by spirometry and impulse oscillometry (IOS) methods. Forty-one postinfectious BO patients (71% male) with a mean age of 106±60 months, followed for a median period of 29 (IQR: 7.5-105.5) months in three different centres were enrolled. Mean age at diagnosis was 41±32 months. Their median z-score of weight was -0,49 (IQR:-2.39-0.67) while median z-score of height was -0,82 (IQR: -1.80-0.35). Mean FEV1 value was 48.8±14.2%, FVC was 56.8±11.9% in 26 patients who could perform spirometry. When the IOS results of BO patients were compared with their spirometry results, percent of resistance values at 5,10,15 and 20 hz (R5, R10, R15 and R20) (p=0.00, 0.00, 0.00 ve 0.01, respectively) and resonance frequency (p=0.00) correlated negatively while reactance values at 5,10,15 and 20 hz (X5, X10, X15 and X20) (p=0.00, 0.01, 0.01, 0.00, respectively) correlated positively with FEV1 results. In conclusion; pulmonary function of children with BO who cannot perform spirometry can be evaluated by IOS method in which only minimal cooperation is needed. ER -