PT  - JOURNAL ARTICLE
AU  - Julia Beeson
AU  - Vladimir Anikin
AU  - Sundeep Kaul
AU  - Dimitrios Kyparissopoulos
AU  - Paras Dalal
TI  - Primary lung cancer treated using radiofrequency ablation: Two year outcome data
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P2719
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P2719.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P2719.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Purpose: Percutaneous image guided radiofrequency ablation (RFA) is increasingly used as an alternative treatment option for patients with inoperable primary lung cancer (NSCLC) but there are little published outcome data. We report safety & efficacy of RFA in patients with NSCLC (stages 1-4) at 1 & 2 years.Methods and Materials: Under general anaesthesia 38 patients, underwent RFA of 50 pulmonary tumours. Survival were evaluated prospectively at 3, 6, 9,12 & 24 months whilst complications was assessed 1 month post procedure.Results: There were no cases of procedure related mortality. Complications included pneumothorax requiring intercostal drain (ICD) insertion (n=20, 53%), small pneumothorax not requiring ICD (n=3, 8%) and pleural effusion (n=2, 5%). One year overall survival and cancer specific (C/S) for tumours classified as Stage 1 (n=20) were 100% and 100% respectively. Stage 2 (n=7) 85% & 100% respectively and stage 4 (n=11) 64% & 73% respectively. Two year survivals (overall & C/S) for Stage 1 were 85% & 95%, in Stage 2 patients 43% & 86% and those at Stage 4 45% & 64% respectively.Conclusion: RFA is a safe, effective and well-tolerated treatment option in patients with inoperable lung cancer. Our study also shows that ablation therapy may be useful in higher stage tumours.