TY - JOUR T1 - The influence of bronchial asthma as a comorbidity of COPD on the COPD assessment test (CAT) JF - European Respiratory Journal JO - Eur Respir J VL - 44 IS - Suppl 58 SP - P1770 AU - Taisuke Jo AU - Yasuhiro Yamauchi AU - Reiko Okudaira AU - Akira Saito AU - Nobuaki Hirota AU - Yasushi Goto AU - Osamu Narumoto AU - Kousuke Watanabe AU - Mitsuhiro Sunohara AU - Yosuke Amano AU - Masafumi Horie AU - Yu Mikami AU - Satoshi Noguchi AU - Hirotaka Matsuzaki AU - Goh Tanaka AU - Kazutaka Takami AU - Nobuya Ohishi AU - Tadashi Kohyama AU - Takahide Nagase Y1 - 2014/09/01 UR - http://erj.ersjournals.com/content/44/Suppl_58/P1770.abstract N2 - Introduction: Bronchial asthma (BA) represents features similar to Chronic Obstructive Pulmonary Disease (COPD). Despite, in intervention study, distinction from one another is required which may lead to a study population dissociated from that we face in clinical practice. The concept that these two disease actually coexist in one airway has become widely accepted. The aim of this study is to see if BA as a comorbidity of COPD has affected the COPD assessment test (CAT). Methods: Records of Total 75 COPD patients who entered the University of Tokyo Hospital from 2012 onwards were analyzed. Results: Out of 20 patients who were diagnosed as having BA alongside with COPD (COPD/BA+) by their respective attending physicians, 16 had inhaled corticosteroid (ICS) when CAT was performed. Ratio of patients who met the criteria of CAT≥10 was 0.60 for both COPD patients without BA (COPD/BA-) and COPD/BA+, 12.7 ± 0.89 (mean ± SEM) and 12.3 ± 1.6, respectively. The ratio was 0.56 (11.9 ± 1.87) for COPD/BA+ with ICS (ICS+) and 0.75 (13.8 ± 3.3) for COPD/BA+ without ICS (ICS-). Whilst, in COPD/BA- patients, it was 0.80 (14.7 ± 1.95) for ICS+ and 0.52 (12.2 ± 1.28) for ICS-. ΔCAT (CAT maximum−CAT minimum) was evaluated for 35 patients whose CAT was followed up for over 6 months. In COPD/BA-, ΔCAT was 7.5 ± 1.91 and 5.93 ± 1.27, for ICS+ and ICS- respectively. In COPD/BA+, it was 5.57 ± 0.48 and 9.33 ± 3.67 for ICS+ and ICS- respectively. Conclusion: Our preliminary data seems to suggest that CAT of COPD/BA+ is more susceptible to ICS compared to COPD/BA-. We will further process this cohort analysis in desire to have a better understanding of COPD patients associated with BA. ER -