RT Journal Article SR Electronic T1 Sensitivity and specificity of neck circumference in obstructive sleep apnea syndrome JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2293 VO 44 IS Suppl 58 A1 Carmen Ardelean A1 Diana Dimitriu A1 Stefan Frent A1 Iosif Marincu A1 Daniel Lighezan A1 Stefan Mihaicuta YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P2293.abstract AB Objectives: A cross-sectional review to assess the ability of the neck circumference(NC) to predict obstructive sleep apnoea syndrome(OSAS) in a population group from Timisoara, Romania.Methods: 836 consecutive adult male patients referred to a sleep lab were polysomnographic evaluated for OSAS between 2005-2013. NC was recorded. With the area under curve(AUC) derived from the receiver-operating characteristic(ROC) curve we assessed the classification ability of NC for the diagnostic of OSAS. Sensitivity, specificity, positive predicted value(PPV), negative predicted value(NPV), positive likelihood ratio(LR+) and negative likelihood ratio(LR-) were calculated for different cut-off points.Results: Age=19-83years; NC=30-62cm. 778(93.1%) patients with OSAS, with apnoea-hypopnea index(AHI)> 5/hour. median AHI=38.75/h.Correlation was found between NC and AHI (ρ=0.35, p<0.001). AUC=0.71 (95% CI 0.63-0.79, p<0.001)[figure1]. The optimal NC was 41 cm, sensitivity=0.8099, specificity=0.5185, PPV=0.9588, NPV=0.1647. LR+=1.68 indicating that a male patient with NC>41 is 1.68 times more likely to have OSASView this table:ROC analysis.Conclusion: NC measurement is easy to obtain with no additional costs. NC is a reliable measurement in patients suspected to have OSAS on a population referred to a sleep lab. Patients with NC of more than 41 cm should have a priority for the overnight sleep study.