PT  - JOURNAL ARTICLE
AU  - Ibrahim Ibrahim
AU  - Ahmed Shawky
AU  - Wesam Ibrahim
TI  - Serum vitamin D levels In patients with asthma
DP  - 2014 Sep 01
TA  - European Respiratory Journal
PG  - P1036
VI  - 44
IP  - Suppl 58
4099  - http://erj.ersjournals.com/content/44/Suppl_58/P1036.short
4100  - http://erj.ersjournals.com/content/44/Suppl_58/P1036.full
SO  - Eur Respir J2014 Sep 01; 44
AB  - Background: It must be obvious that no one factor should be held accountable for the aetiology of allergic diseases, asthma or acute asthma exacerbations. Operating on a genetic basis many factors must play a role. It has been postulated that vitamin D deficiency, as a result of industrialization and Westernized lifestyles that have led to sun-avoidance behaviors and more time indoors, has a role in the development of asthma and allergies. Objective:To assess the relationship between serum vitamin D levels and severity Of asthma.Patients and Methods: The study will be carried on 30 patients with atopic asthma, divided into three groups according to severity of airway obstruction, and ten healthy control subjects. Serum 25-hydroxyvitamin D3 [25(OH) D], a vitamin D metabolite, was measured using an immunodiagnostic ELISA technique. Results: 35% of all subjects were vitamin D insufficient, as defined by a level ≤ 30 ng/ml 25(OH) vit D. Mean vitamin D levels were lowest in patients with severe asthma.View this table:Tab.1 Serum Vit.D levels (ng/ml) in the studied groups.Conclusion: Vitamin D insufficiency is common in patients with asthma, and is associated with the degree of asthma severity.