RT Journal Article SR Electronic T1 Association between typhoon and asthma control JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4055 VO 44 IS Suppl 58 A1 Yasuhito Suzuki A1 Suguru Sato A1 Junpei Saito A1 Atsuro Fukuhara A1 Manabu Uematsu A1 Kenichi Misa A1 Takefumi Nikaido A1 Naoko Fukuhara A1 Xintao Wang A1 Yoshinori Tanino A1 Takashi Ishida A1 Mitsuru Munakata YR 2014 UL http://erj.ersjournals.com/content/44/Suppl_58/P4055.abstract AB Objectives:It is well-known that climate changes during a typhoon season make asthma control worse. Several hypotheses such as pollen rapture, changes in temperature and atmospheric pressure could be considered. The aim of the study is to evaluate associations between typhoon, allergic sensitization, and asthma control.Methods:Sixty one asthmatic subjects were interviewed whether they were aware of any symptom changes during a typhoon season in Japan (between September and October). Subjects were divided into 2 groups according to the presence or absence of symptom changes. Then, clinical characteristics, sensitization to allergens, asthma control test (ACT), fractional exhaled nitric oxide (FeNO) levels, WBC, Eosinophils, lung functions were compared between groups. Patients were excluded if they had hazy memories or other respiratory comorbidity other than asthma, and if their treatments were changed during the season.Results:Three subjects were excluded because of the exclusion criteria. Seventeen of 58 patients (29%) realised their symptom changes (worsen group). Total IgE levels, cedar-specific IgE levels and the proportion of short course treatment with oral corticosteroids for exacerbation in the past one year were significantly higher in worsen group compared to subjects without symptom changes (p=0.03).Conclusions:Pollen sensitisation could be related to one of the factors in worsening asthma symptoms during the typhoon season.