%0 Journal Article %A Yasuhito Suzuki %A Suguru Sato %A Junpei Saito %A Atsuro Fukuhara %A Manabu Uematsu %A Kenichi Misa %A Takefumi Nikaido %A Naoko Fukuhara %A Xintao Wang %A Yoshinori Tanino %A Takashi Ishida %A Mitsuru Munakata %T Association between typhoon and asthma control %D 2014 %J European Respiratory Journal %P P4055 %V 44 %N Suppl 58 %X Objectives:It is well-known that climate changes during a typhoon season make asthma control worse. Several hypotheses such as pollen rapture, changes in temperature and atmospheric pressure could be considered. The aim of the study is to evaluate associations between typhoon, allergic sensitization, and asthma control.Methods:Sixty one asthmatic subjects were interviewed whether they were aware of any symptom changes during a typhoon season in Japan (between September and October). Subjects were divided into 2 groups according to the presence or absence of symptom changes. Then, clinical characteristics, sensitization to allergens, asthma control test (ACT), fractional exhaled nitric oxide (FeNO) levels, WBC, Eosinophils, lung functions were compared between groups. Patients were excluded if they had hazy memories or other respiratory comorbidity other than asthma, and if their treatments were changed during the season.Results:Three subjects were excluded because of the exclusion criteria. Seventeen of 58 patients (29%) realised their symptom changes (worsen group). Total IgE levels, cedar-specific IgE levels and the proportion of short course treatment with oral corticosteroids for exacerbation in the past one year were significantly higher in worsen group compared to subjects without symptom changes (p=0.03).Conclusions:Pollen sensitisation could be related to one of the factors in worsening asthma symptoms during the typhoon season. %U