PT  - JOURNAL ARTICLE
AU  - Lamia Ouanes-Besbes
AU  - Saoussen BenAbdallah
AU  - Islem Ouanes
AU  - Fahmi Dachraoui
AU  - Fekri Abroug
TI  - Effects of home ventilation on survival: Comparison in obstructive and restrictive diseases
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P2476
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P2476.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P2476.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Home ventilation proved effective in prolonging life in patients suffering from restrictive respiratory disease. It has recently been proposed in obstructive disease especially in patients with frequent exacerbations. We report in this study our experience with home ventilation emphasizing its impact on survival in obstructive compared to restrictive patients.Patients and methods: Starting from 2005, 82 patients (50% males, mean age: 62±15 years) were prescribed home ventilation via facial/nasal mask and included in the present analysis. A survival analysis with LogRank test was made after a mean follow-up of 29±16 months.Results: 48 patients had obstructive disease either isolated (n=20), or associated with obstructive sleep apnea (Overlap syndrome, n=28). The remaining 34 had restrictive pulmonary disease (mainly myopathy). At time of censoring, 70 patients were still alive. There was no statistical difference in cumulated survival between obstructive and restrictive patients (LogRank= 0.3).CONCLUSION: Our study shows similar survival patterns with home ventilation in obstructive and restrictive respiratory failure. The impact on quality of life should be compared too.