@article {FournierP2227, author = {Marie-C{\'e}cile Fournier and Thomas Lesuffleur and Alexandre Touvron and Michel Cabillic and Arnaud Cavailles and Jean-Benoit Hardouin and Arnaud Chambellan}, title = {Factors of improvement of dyspnoea, exercise capacity, and quality of life in COPD patients undergoing an outpatient pulmonary rehabilitation}, volume = {42}, number = {Suppl 57}, elocation-id = {P2227}, year = {2013}, publisher = {European Respiratory Society}, abstract = {Pulmonary rehabilitation (PR) represents the optimal way to improve COPD patients, but inclusion criteria of success remain challenging.Aim: to identify factors of improvement of patients at the beginning of an outpatient PR.Methods: 94 consecutive COPD patients were included. After complete assessment, they underwent a 3 week{\textquoteright}s physical training and therapeutic education at the hospital. This was followed by 20 physical sessions supervised by the patient{\textquoteright}s physiotherapist. The patients were evaluated at 6 months and one year. The logistic regression was used to identify the independent predictors of success to PR, defined by the MCID for dyspnoea (mMRC scale), the 6 minute walk distance (6MWD), and the Saint George{\textquoteright}s Respiratory Questionnaire (SGRQ) total score at baseline.Results: Patients who improve the mMRC scale had a higher level of dyspnoea (OR=4.92, 2.35 to 10.32 CI 95\%), were treated by tiotropium (OR=6.43, 1.71 to 24.10), were not frequent exacerbators (OR=4.04, 1.27 to 12.88), and reached a higher VO2max (OR=1.09, 1.04 to 1.15). The only variable identified for 6MWD improvement was not to live alone (OR=9.19, 1.16 to 73.02). Patients who improve the SGRQ score had a higher FEV1 (OR=1.06, 1.01 to 1.11), a higher level of dyspnoea (OR=2.12, 1.05 to 4.28), a worse SGRQ score (OR=1.11, 1.04 to 1.18), a lower CRP (OR=4.07, 1.15 to 14.39), and were more prone to have a 6MWD\>350 m (OR=9.72, 1.92 to 49.24).Conclusion: Predictors of improvement in COPD patients undergoing an outpatient PR differ from each dimension. They should be evaluated separately with the patient{\textquoteright}s perspectives to better define the components of success to PR.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/42/Suppl_57/P2227}, eprint = {https://erj.ersjournals.com/content/42/Suppl_57/P2227.full.pdf}, journal = {European Respiratory Journal} }