PT  - JOURNAL ARTICLE
AU  - Tore Amundsen
AU  - Peter Hatlen
AU  - Sven Carlsen
AU  - Oyvind Salvesen
AU  - Arnulf Langhammer
TI  - Cardiovascular disease and the risk of lung cancer, the HUNT study
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - 4636
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/4636.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/4636.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - Background: Inflammation is involved in both lung cancer (LC) and cardio-vascular disease (CVD).Aims: We hypothesize that CVD is an independent risk factor for LC.Methods: Data from the Nord-Trøndelag Health Study linked to the Norwegian Cancer and Death Cause Registry, analyses stratified by smoking. 97,087 persons (1,634,967 person years), never smokers n=38,656, former smokers n=20,914, current smokers n=26,894, follow-up 15 years. The proportional hazard model (HR CI 95%) for CVD on LC incidence, adjusted for age, sex, BMI, burden of smoking and chronic cough. Results: LC = 1,080, cases (1.1%), CVD = 5,981 (6.9%). CVD vs LC in former smokers = HR 1.74 (CI95% 1.11-273), current smokers = HR 1.38 (CI95% 1.04-1.83), never smokers = HR 0.87 (CI95% 03.4-2.23).View this table:Table 1Conclusion: CVD was an independent risk factor for lung cancer in former and current smokers. CVD may be a novel risk factor for lung cancer screening.