RT Journal Article SR Electronic T1 Assessment of daily activity in COPD JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1832 VO 42 IS Suppl 57 A1 Ali Albarrati A1 Nichola Gale A1 Stephanie Enright A1 Iain Munnery A1 Margaret Munnaery A1 John Cockcroft A1 Dennis Shale YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P1832.abstract AB BackgroundPatients with COPD have progressive loss of daily physical activity; however, its measurement is limited to research settings. A simple measure of physical activity in the elderly is the Timed Up and Go (TUG) test. We hypothesised that the TUG could provide an estimation of daily physical activity in COPD.MethodAs part of the ARCADE study, daily physical activity was monitored for a week, using a multisensor armband (SenseWear Pro armband), in 49 patients and 29 comparators. Spirometry, body composition, six minute walk distance (6MWD) and TUG test were also determined.ResultsPatients and comparators were similar in age, BMI and gender, but differed in number of steps, 6MWD and TUG (Table1). In patients, the number of steps related to TUG (r=-0.52, p=0.001), FEV1% (r=0.48, p=0.001), 6MWD (r=0.68, p=0.001). The total energy expenditure related to 6MWD in patients (r=0.42, p=0.004) and comparators (r=0.39, p=0.04), but only to TUG in patients (r=-0.37, p=0.01). In COPD, stepwise regression analysis, adjusted for age, gender and BMI showed that TUG test, and FEV1% explained 39% of the variance in number of steps and 57% of the variance in 6MWD.ConclusionThe TUG test is an integrated test of gait speed, balance and functional capacity which appears to predict daily physical activity in COPD. As a simple rapid test, the TUG test may be a useful indicator of daily physical performance in clinical practice.View this table:Clinical characteristics of patients and comparators