@article {LondheP4908, author = {Jyoti Londhe and Bill Brashier and Neha Iyer and Sapna Madas and Sanjay Juvekar and Sundeep Salvi and Peter Barnes}, title = {Comparison of quality of life in smoking and non-smoking COPD patients in India using St. George{\textquoteright}s respiratory questionnaire and COPD assessment test}, volume = {42}, number = {Suppl 57}, elocation-id = {P4908}, year = {2013}, publisher = {European Respiratory Society}, abstract = {Quality of life (QoL) assessment is an integral part of disease management and prognosis for all chronic illnesses, including COPD. Non-smoking (NS) COPD accounts for 25-45\% of all COPD cases globally, and is relatively more common in India. There is little information on QoL of NS-COPD patients and how it compares with smoking (S)-COPD. We studied the QoL of NS-COPD using SGRQ and CAT and compared it with S-COPD. Methods: 80 smoking \& 77 non-smoking physician-confirmed COPD patients with a post-bronchodilator FEV1/FVC\<70\% were administered SGRQ and CAT using validated locally translated questionnaires. Results: There were no differences in the age and mean FEV1 of S-COPD and NS-COPD (41.0\% {\textpm} 13.3 vs 42.9\% {\textpm} 17.4; p=ns). The mean total SGRQ \& CAT scores were similar in both the COPD groups (SGRQ: 60.7{\textpm}18.1 vs 62.6{\textpm}18.5; p=0.51) (CAT: 23.7{\textpm}7.3 vs 23.5{\textpm}8.0; p=0.86). NS-COPD had lesser symptom SGRQ scores and had lesser CAT scores for cough compared with S-COPD (SGRQ 43.6{\textpm}24.2 Vs 52.5{\textpm}21.4; p=0.01 and CAT 2.5{\textpm}1.3 Vs 3.0{\textpm}1.4; p=0.02). When divided into moderate, severe and very severe COPD, NS-COPD and S-COPD showed similar SGRQ and CAT scores (p\>0.05). There was a strong correlation between SGRQ and CAT scores for both NS-COPD (r2= 0.54, p=0.0001) and S-COPD (r2= 0.67, p=0.0001). Interestingly, the SGRQ scores are higher in Indian patients than in Western patients for equivalent FEV1 values. Conclusion: Impairment of QoL of NS-COPD is similar to S-COPD in an Indian cohort.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/42/Suppl_57/P4908}, eprint = {https://erj.ersjournals.com/content/42/Suppl_57/P4908.full.pdf}, journal = {European Respiratory Journal} }