TY - JOUR T1 - Efficacy of corticosteroids in hospital treated community-acquired pneumonia JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P402 AU - Perlat Kapisyzi AU - Dhimitraq Argjiri AU - Anila Aliko AU - Loreta Bica AU - Jeta Beli AU - Ylli Vakeflliu AU - Elenka Shehu AU - Roland Kore AU - Holta Tafa AU - Ornela Nuredini AU - Regina Hasa AU - Mirela Tabaku AU - Eritien Tashi AU - Edlira Ndreu AU - Esmeralda Nushi AU - Arben Tanka AU - Epaminonda Fype Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P402.abstract N2 - The Aim : The aim of the study was to eveluate benefical effect of corticosterides in short treatment of community acquired pneumonia (CAP).Patients and Methods: We enrolled a total of 149 hospitalized patients, for a period of an year (Januay 2011 to Decembre 2011). The diagnose of CAP was made using standard clinical and radiological criteria. Disease severity was scored using Pneumonia Severity Index. Age, antibiotic treatment and PSI adjustement has been done between the groups. Patients received 50 mg prednisolone for 7 days, along with antibiotics.The outcomes were clinical cure at day seven, defervescence, length of stay, time to clinical stability,Results: Mean age of patients enrolled in study was 63±16.7 in prednisolone and 53±18.6 in group without prednisolone Therty (40 %) patients in prednisolone group and 16(22.2%) in without prednisolone group were in Peumonia Severity Index class IV-V. Clinical cure at days 7 was 61/75 (82.6%) in the prednisolone group and 44/72 (61.1%) in other group.[P < 0.008). Patients on prednisolone had faster defervescence compared with other group, (p<0.0032). Length of stay was significally lower in patients with prednisolone compared with nonprednisolone group, 9.4±4.33 and 12.3±6.4 respectively, (p=0.0011). Adverse events were few and not different between the two groups.Conclusions: In this study we show that Prednisolone (at 50 mg) once daily for a short time, (a week), have a beneficial effects in patients hospitalized with mild to severe CAP, improving outcomes without adverse events. ER -