RT Journal Article
SR Electronic
T1 External multicentric validation of a COPD detection questionnaire
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3969
VO 40
IS Suppl 56
A1 Miguel Bergna
A1 Gabriel Garcia
A1 Ramon Alchapar
A1 Hector Altieri
A1 Oscar Caberlotto
A1 Juan Figueroa Casas
A1 Luis Larrateguy
A1 Luis Nannini
A1 Pedro Grabre
A1 Gustavo Zabert
A1 Daniel Paskansky
A1 Sebastian Fucile
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P3969.abstract
AB Introduction: Chronic obstructive pulmonary disease (COPD) is a preventable disease. The development of a simple questionnaire can help to improve the diagnosis. Objective: External validation of the questionnaire to detect COPD in Argentina. Material and Methods: We were performed a questionnaire in subjects with over 40 years old and history of smoking ≥ 10 or more pack / year. Demographic data and pre and post bronchodilator spirometry were performed. Subjects with previous diagnosis of COPD or asthma were excluded.Results. 468 subjects were evaluated.100 (21.1%) had spirometric diagnosis of COPD. In univariate analysis patients with COPD had higher median age (58 years vs 54 years, p <0.001), pack years (PY) smoked (40 vs 30, P <0.001), lower BMI (26 vs 28, P = 0.02), higher incidence of males (68.8% vs 43.9%, P <0.001), cough for 3 months (55.2% vs 35.8%, P = 0.001), chronic cough (47.9% vs 28.8%, P <0.001), phlegm for 3 months (50% vs 37.2, P = 0.02), chronic phlegm (40.6% vs 26.1%, P = 0.005), dyspnea (62.5% vs 51.9%, P = 0.06), wheezing (55.2% vs 47%, P = 0.15), wheezing without infection (38.5% vs 33.9%, P = 0.39), stove at home (10.4% vs 7.5%, P = 0.35) and risk profession (19.8% vs 18.5 %, P = 0.78).The presence of at least 3 of these variables had a sensitivity of 95% and a specificity of 25.29%, positive predictive value (PPV) of 22.62% and negative (NPV) of 95.65%. The presence of at least 6 variables had a sensitivity of 90% and a specificity of 70.97%, a PPV of 50% and a NPV of 95.65%Conclusion This simple questionnaire for demographic and clinical data can be useful for detection of COPD.