TY - JOUR T1 - External multicentric validation of a COPD detection questionnaire JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P3969 AU - Miguel Bergna AU - Gabriel Garcia AU - Ramon Alchapar AU - Hector Altieri AU - Oscar Caberlotto AU - Juan Figueroa Casas AU - Luis Larrateguy AU - Luis Nannini AU - Pedro Grabre AU - Gustavo Zabert AU - Daniel Paskansky AU - Sebastian Fucile Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P3969.abstract N2 - Introduction: Chronic obstructive pulmonary disease (COPD) is a preventable disease. The development of a simple questionnaire can help to improve the diagnosis. Objective: External validation of the questionnaire to detect COPD in Argentina. Material and Methods: We were performed a questionnaire in subjects with over 40 years old and history of smoking ≥ 10 or more pack / year. Demographic data and pre and post bronchodilator spirometry were performed. Subjects with previous diagnosis of COPD or asthma were excluded.Results. 468 subjects were evaluated.100 (21.1%) had spirometric diagnosis of COPD. In univariate analysis patients with COPD had higher median age (58 years vs 54 years, p <0.001), pack years (PY) smoked (40 vs 30, P <0.001), lower BMI (26 vs 28, P = 0.02), higher incidence of males (68.8% vs 43.9%, P <0.001), cough for 3 months (55.2% vs 35.8%, P = 0.001), chronic cough (47.9% vs 28.8%, P <0.001), phlegm for 3 months (50% vs 37.2, P = 0.02), chronic phlegm (40.6% vs 26.1%, P = 0.005), dyspnea (62.5% vs 51.9%, P = 0.06), wheezing (55.2% vs 47%, P = 0.15), wheezing without infection (38.5% vs 33.9%, P = 0.39), stove at home (10.4% vs 7.5%, P = 0.35) and risk profession (19.8% vs 18.5 %, P = 0.78).The presence of at least 3 of these variables had a sensitivity of 95% and a specificity of 25.29%, positive predictive value (PPV) of 22.62% and negative (NPV) of 95.65%. The presence of at least 6 variables had a sensitivity of 90% and a specificity of 70.97%, a PPV of 50% and a NPV of 95.65%Conclusion This simple questionnaire for demographic and clinical data can be useful for detection of COPD. ER -