RT Journal Article
SR Electronic
T1 Comorbidity in chronic obstructive pulmonary disease (COPD): Data from the fourth Korean National Health and Nutrition Examination Survey (KNHANES IV)
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P456
VO 40
IS Suppl 56
A1 Moon, Chansoo
A1 Kim, Sae Byol
A1 Chung, Kyung Soo
A1 Park, Seon Cheol
A1 Jung, Won Jai
A1 Kim, Eun Young
A1 Jung, Ji Ye
A1 Kang, Young Ae
A1 Park, Moo Suk
A1 Kim, Young Sam
A1 Kim, Se Kyu
A1 Ahn, Chul Min
A1 Chang, Joon
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P456.abstract
AB Introduction: Many comorbidities frequently coexist with chronic obstructive pulmonary disease (COPD) and they could influence on poor prognosis. We tried to determine which comorbidities frequently coexist in individuals with COPD using population based nationwide survey.Method: We used data obtained in the first (2007) and second year (2008) of the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV) and included participants aged ≥40 years. Subjects with FEV1/FVC<0.7 was defined as individuals with COPD. Participants with history of asthma, pulmonary tuberculosis and bronchiectasis were excluded.Result: Baseline characteristics were not significantly different between COPD group (n=357) and control group (n=357) except spirometric findings. COPD group was associated with increased risk of low BMI (<18.5 Kg/m2) (OR 3.53, 95% CI 1.29-9.68; p=0.014) and associated with decreased risk of hypertension (OR 0.73, 95% CI 0.54-0.99; p=0.042) and hypercholesterolemia (OR 0.59, 95% CI 0.37-0.93; p=0.022). The incidence of low BMI uniquely increased with the severity of airflow obstruction (1.4% in control subjects, 3.6% in GOLD stage I, 4.5% in GOLD stage II and 30% in GOLD stage III+; p<0.0001). However, the incidence of hypertension and hypercholesterolemia did not.Conclusion: Incidence of low BMI uniquely increased with the severity of airflow limitation. However, more study is needed to confirm whether low BMI is the cause of COPD or the result of COPD.