PT  - JOURNAL ARTICLE
AU  - Ekaterina Kochetova
TI  - Densitometric diagnosis of osteoporosis in patients with chronic obstructive pulmonary disease
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P541
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P541.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P541.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - The aim of the Study: to study the state of bone mineral density (BMD) in patients with chronic obstructive pulmonary disease (COPD). Materials and methods: studied 104 patients with COPD. The study group comprised men with long smoking history. Mean age 61,2 ± 5,7 years. The study of respiratory function was performed on a multi-type installation «Master-Lab/Jaeger». The study of bone mineral density (BMD) of lumbar spine and proximal femur was performed by X-ray absorptiometry at the densitometer «Lunar DPX-NT». The frequency of osteoporosis was assessed in the whole group and separately for each stage of COPD. Results: In the whole group was most impressed by osteoporosis, lumbar spine - in 37,2% of cases, osteoporosis of the femoral neck - in 19,77% of cases. The lowest BMD were observed in patients with stage 4 COPD (p <0,05). Osteoporosis of the femoral neck was detected in 5,4% of patients with COPD stage 2, with 23,68% of patients with COPD stage 3, the maximum percentage of osteoporotic changes in the femoral neck was observed in patients with COPD 4 stage - 54,5%. A significant correlation values of bone mineral density with BMI (r 0,44, p <0,05), with the DLCO (r 0,43, p <0,01). Conclusion: densitometry is an important method of diagnostics of osteoporosis and should be applied in full in COPD patients.