RT Journal Article
SR Electronic
T1 Antituberculosis drug resistance rates in patients newly diagnosed with TB in Istanbul
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2681
VO 40
IS Suppl 56
A1 Ogun Sezer
A1 Faruk Ciftci
A1 Erkan Bozkanat
A1 Tuncer Ozkisa
A1 Hatice Kaya
A1 Tuba Ursavas
A1 Zafer Kartaloglu
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P2681.abstract
AB Background: Our hospital serves about 70% of all patients with tuberculosis (TB) in Turkish Armed Forces.Aim: To assess drug resistance rates in soldier new patients with TB followed in our hospitalMethod: Culture positive all new patients admitted to hospital between 1st of December 2006 and 1st of August 2010 enrolled into the study. 28 cases thought as relapse excluded the study. Drug susceptibilities in all patients were determined with BACTEC 460 TB.Results: Drug susceptibility test was performed in 302 cases. Of all were men. Mean age was 21,7±2,1 years. 235 patients had smear and culture positivity. 67 had only culture positivity. 16 patients with pleural TB had culture positivity. 17,2% of all cases had at least one drug resistance. Isoniazid (H), streptomycine (S), rifampicin (R), and ethambutol (E) resistance rates were 14,3%, 1,9%, 4,6%, and 5,6% (respectively). 14 cases (4,6%) had multidrug resistance (H+R). H+S resistance was 0,7%. H+E resistance was 0,3%. H+R+E resistance was 1,5%. H+R+E+S resistance was 1,8%Conclusion: In soldier patients, who are strongly representative of the young population in Turkey, H resistance was high. Others were acceptable levels.