PT  - JOURNAL ARTICLE
AU  - Ogun Sezer
AU  - Faruk Ciftci
AU  - Erkan Bozkanat
AU  - Tuncer Ozkisa
AU  - Hatice Kaya
AU  - Tuba Ursavas
AU  - Zafer Kartaloglu
TI  - Antituberculosis drug resistance rates in patients newly diagnosed with TB in Istanbul
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P2681
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P2681.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P2681.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Background: Our hospital serves about 70% of all patients with tuberculosis (TB) in Turkish Armed Forces.Aim: To assess drug resistance rates in soldier new patients with TB followed in our hospitalMethod: Culture positive all new patients admitted to hospital between 1st of December 2006 and 1st of August 2010 enrolled into the study. 28 cases thought as relapse excluded the study. Drug susceptibilities in all patients were determined with BACTEC 460 TB.Results: Drug susceptibility test was performed in 302 cases. Of all were men. Mean age was 21,7±2,1 years. 235 patients had smear and culture positivity. 67 had only culture positivity. 16 patients with pleural TB had culture positivity. 17,2% of all cases had at least one drug resistance. Isoniazid (H), streptomycine (S), rifampicin (R), and ethambutol (E) resistance rates were 14,3%, 1,9%, 4,6%, and 5,6% (respectively). 14 cases (4,6%) had multidrug resistance (H+R). H+S resistance was 0,7%. H+E resistance was 0,3%. H+R+E resistance was 1,5%. H+R+E+S resistance was 1,8%Conclusion: In soldier patients, who are strongly representative of the young population in Turkey, H resistance was high. Others were acceptable levels.