PT  - JOURNAL ARTICLE
AU  - Fumitaka Ito
AU  - Yasushi Ohno
AU  - Koumei Yanase
AU  - Fumihiko Kamiya
AU  - Hidenori Mori
AU  - Junki Endo
AU  - Norihiko Funaguchi
AU  - Masanori Kawasaki
AU  - Shinya Minatoguchi
TI  - Relationship between qualitative analysis of lung tumors using integrated backscatter-intravascular ultrasound (IB-IVUS) and pathological diagnosis
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P4402
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P4402.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P4402.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Introduction or background:End-bronchial ultrasound is used by a supersonic wave image to confirm the position relations of a tumor and the participation bronchus through a bronchoscope. However, the diagnosis of the organization property of the tumor is difficult. We used integrated backscatter(IB) value which analyzed the reflection wave of the supersonic wave signal in the coronary arteries of human, and was calculated, and enabled a vascular wall organization property diagnosis.Aims and objectives:The purpose of the study measures integrated backscatter (IB) by end-bronchial ultrasound for the diagnosis of the lungs tumor and analyzes it by comparing a tumor and the distinction of the normal tissue with surgical resection.Methods:We analyzed lungs tumor and normal lungs organization provided from an operation specimen. We observed relations with the structure of the organization about the lungs tumor.Result:Surgery excision lungs tumor were 35 non-small-cell lung cancer (squamous cancer 9 examples, non-squamous cancer 26 examples). IB value showed lower value in non-small cell lung cancer tissue compaired with normal lung tissue. The necrosis had low IB value, and IB value showed a high value at fibrosis tissue.High cell density tumor showed lower IB level than low cell density tumor.Conclusion:If the distinction of the normal tissue and tumor tissue is possible and applies it to an endoscopic diagnosis by measuring lungs tumor, normal lung, IB value of the pathology organization diagnosis and invasive level of the tumor may be enabled by bronchus endoscope echo examination.