TY - JOUR T1 - Adverse drug reactions in a pulmonary teaching hospital: Incidence, pattern, seriousness, and preventability JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p3609 AU - Shadi Baniasadi AU - Fanak Fahimi AU - Masoome Karimi Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p3609.abstract N2 - Introduction: Detection of adverse drug reactions (ADRs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. Studies have shown that between 1.7% and 25.1% of hospital inpatients experience an ADR during their hospitalization.Aims: This study aimed to determine the incidence, pattern, seriousness, and preventability of hospital-acquired ADRs, in medical wards of a pulmonary teaching hospital in Iran.Methods: Clinical pharmacist residents were trained to report all suspected ADRs through ADR-reporting yellow forms. The incidence, pattern, seriousness, and preventability of the reported ADRs were analysed.Results: During the period of 24 months, for 16125 patients, 312 ADR reports were received. The most frequently reported reactions were due to anti-infective agents (26.54%). Ceftriaxone accounted for the highest number of the reported ADRs among anti-infective agents. The gastro-intestinal system was the most frequently affected system (21.78% of all reactions). Eighteen percent of the ADRs were reported as serious reactions. Fifty of the ADRs were classified as preventable.Conclusions: Our study shows that ADRs are an important cause of morbidity in our hospital. Disease prevalence and drug use patterns in our hospital differ markedly from those of generalized ones. These differences affect the frequency and nature of ADRs. Preventive measures should be taken to minimize the occurrence of ADRs. ER -