PT  - JOURNAL ARTICLE
AU  - J.L. Lobo
AU  - P. Sobradillo
AU  - I. Obieta-Fresnedo
AU  - A. Rivas
AU  - R. Valle
AU  - C. Navarro
AU  - D. Jimenez
TI  - TAPSE as a prognostic factor in hemodinamically stable pulmonary embolism
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p2347
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p2347.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p2347.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Introduccion: Right Ventricular Dysfunction (RVD) is a predictor of mortality in Pulmonary Embolism. The reproducibility of classic parameters is low. The TAPSE is easier and more reproducible.Aim: To asses whether TAPSE has prognostic value in patients with PE.Methods: PROTECT is a multicentric study of patients with hemodynamically stable PE; evolution data were gathered through 30 days. Echocardiography in the first 48 hours. RVD criteria: 1) RVEDD >30; 2) RV/LV >1.0; 3) hypokinesia subjectively evaluated; or 4) TR jet >2.8 m/s. Statistical analysis with SPSS (v. 15). Means were compared with T-Student for quantitative variables; Chi-square for qualitative. OR and corresponding 95CI calculated with univariate logistic regression. Multivariate analysis could not be carried out due to the low number of events.Results: The study included 630 patients. Global mortality was 3,8%, and mortality due to PE was 0,8%. TAPSE could be determined in 91,7% of the patients. Only 16% showed an abnormal TAPSE (≤15). Univariate analysis for 30-day mortality is shown in the table.View this table:Table 1. Univariate analysis for 30 days mortality in the 550 patients without atrial fibrillationConclusions: 1. The probability of dying of PE in the first month is multiplied by more than 20 in patients with a TAPSE ≤ 15. 2. The strength of the association seems clearly superior to the classic echocardiographic parameters of right ventricle dysfunction.