RT Journal Article
SR Electronic
T1 Evolution of lung function in preterm infants with or without bronchopulmonary dysplasia
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p1112
VO 38
IS Suppl 55
A1 Sanchez-Solis, Manuel
A1 Garcia-Marcos, Luis
A1 Perez, Virginia
A1 Pastor, Maria Dolores
A1 Mondejar, Pedro
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p1112.abstract
AB Introduction: Healthy preterm infants do no catch-up lung function (LF) during the first two years of life. The aim of study is to compare the evolution of LF in infants born preterm, with and without BPD.Methods: Forced vital capacity (FVC), forced expiratory flows at 50%, 75%, 25-75% of FVC (FEF50, FEF75, FEF25-75) and forced expiratory flow at 0.5 sec (FEV0.5), was obtained by raised volume rapid torachoabdominal compression technique (RVRTC) in 14 (7 males) BDP+ and in 12 (6 males) infants born preterm BPD-. Measurements were repeated at 6 and 12 moths after baseline. A generalized estimating ecuations (GEE) adjusted for gestational age, length, corrected age and body mass index z-score (according OMS tables) was built for boys and girls separately.Results:View this table:Table 1. Characteristics of BPD+View this table:Table 2. GEE coefficients of LF parameters of infants born preterm BPD+ (base: BPD–)Conclusions: FVC, FEF25-75 and FEV0.5 decrease among male infants with BPD as compared to those without BPD; however in female infants they tend to be similar, and FEF50, FEF25-75 and FEV0.5/FVC even improve.