PT  - JOURNAL ARTICLE
AU  - Labrini Damianidou
AU  - Maria Eboriadou
AU  - Andreas Giannopoulos
AU  - Katerina Haidopoulou
AU  - Irini Tzimou
AU  - Ioannis Tsanakas
AU  - Fani Athanasiadou
TI  - The impact of obstructive sleep apnea syndrome on cardiovascular system in children
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p1751
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p1751.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p1751.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Introduction: Obstructive Sleep Apnea Syndrome (OSAS) has been shown to be an independent risk factor for cardiovascular disease in adults. However, few data are known about the effect of OSAS on cardiovascular system in children.Aims: To investigate clinical and laboratory parameters associated with cardiovascular disease in children with OSAS.Methods: Seventeen subjects, aged 5 to 12 years (mean age 9,24±2,19 years), referring for evaluation of systematic snoring (≥4 nights/week), underwent overnight polysomnography,evaluation of blood pressure, lipidaemic profile and complete echocardiographic assessment. According to the Apnea Hypopnea Index (AHI) subjects were divided into three groups: A. primary snoring (AHI<1, n=1), B. mild OSAS (AHI= 1-5, n=12), C. moderate-severe OSAS (AHI >5, n=4).Results: There were no significantly differences in age, sex, heart rate, systolic and diastolic blood pressure and lipidaemic profile among the groups (p≥0.05).Right ventricular dimension (Right Ventricular end-Diastolic dimension -RVDd) and left ventricular dimensions (Left Ventricular end-Diastolic dimension – LVDd, Left Ventricular diastolic mass – LVdmass, Left Ventricular Posterior Wall diastolic –LVPWd, IntraVenticular Septum diastolic – IVSd)), were not statistically significant different between the three groups and were within normal limits. RVDd was higher in OSAS patients (p=0,096) than in controls.Conclusion: The present study suggests that young patients with systematic snoring have no echocardiographic evidences of cardiac dysfunction. Nevertheless, there is a correlation of increased right ventricular dimension, although not statistically significant, in patients with OSAS.