RT Journal Article
SR Electronic
T1 The application of bi-level positive airway pressure in patients with severe pneumonia and acute respiratory failure caused by influenza A (H1N1) virus
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2076
VO 38
IS Suppl 55
A1 Wei, Liu
A1 Peng, Liping
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2076.abstract
AB Objective: To evaluate the effect of noninvasive Bi-level Positive Airway Pressure (BiPAP) ventilation on the severe influenza A virus associated with pneumonia and acute respiratory failure (ARF).Methods: Based on conventional therapy via face mask using BiPAP ventilator positive airway pressure ventilation in the treatment of severe pneumonia caused by influenza A (H1N1) virus with acute respiratory failure (ARF) in 18 cases, we observed and evaluated the therapeutic effects.Results: PaO2 and SaO2 before and after treatment were (48.85±12.15)mmHg, (68.56±16.25) mmHg and (80±6)%, (92±5)%, respectively. The results were significantly different (P <0.05) before and after treatment. Endotracheal intubation rate was 25% (6/24) and case-fatality rate was 8.3% (2/24).Conclusion: BiPAP ventilator airway pressure by face mask ventilation can reduce the rate of endotracheal intubation in the treatment of severe pneumonia caused by influenza A (H1N1) virus in acute respiratory failure. It could be an effective approach in the emergency treatment with clinical value.