PT  - JOURNAL ARTICLE
AU  - Liu Wei
AU  - Liping Peng
TI  - The application of bi-level positive airway pressure in patients with severe pneumonia and acute respiratory failure caused by influenza A (H1N1) virus
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p2076
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p2076.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p2076.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Objective: To evaluate the effect of noninvasive Bi-level Positive Airway Pressure (BiPAP) ventilation on the severe influenza A virus associated with pneumonia and acute respiratory failure (ARF).Methods: Based on conventional therapy via face mask using BiPAP ventilator positive airway pressure ventilation in the treatment of severe pneumonia caused by influenza A (H1N1) virus with acute respiratory failure (ARF) in 18 cases, we observed and evaluated the therapeutic effects.Results: PaO2 and SaO2 before and after treatment were (48.85±12.15)mmHg, (68.56±16.25) mmHg and (80±6)%, (92±5)%, respectively. The results were significantly different (P <0.05) before and after treatment. Endotracheal intubation rate was 25% (6/24) and case-fatality rate was 8.3% (2/24).Conclusion: BiPAP ventilator airway pressure by face mask ventilation can reduce the rate of endotracheal intubation in the treatment of severe pneumonia caused by influenza A (H1N1) virus in acute respiratory failure. It could be an effective approach in the emergency treatment with clinical value.