RT Journal Article SR Electronic T1 Management and follow up of non-tuberculosis mycobacteria pulmonary infection in 55 infected cases in Iran JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p4378 VO 38 IS Suppl 55 A1 Parvaneh Baghaei Shiva A1 Payam Tabarsi A1 Majid Marjani A1 Mohammad Reza Masjedi YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p4378.abstract AB Background: Non-Tuberculosis Mycobacteria (NTM) are increasing worldwide. This study defines type and outcome of treatment in a referral center in TehranMethods: Study was done in national referral center in Tehran during 2002-2009. All patients with documented NTM pulmonary diseases (based on ATS criteria) were included in study. Patient's data and treatment outcomes were extracted from medical records.Results: 55 patients with NTM pulmonary disease were diagnosed. Female were predominant (52.7%).Mean age was 54.43±15.61.History of smoking was present in 17 (30.9%) and 9 (16.4%) were opium addicted. only one patient was HIV positive.The most common type was Mycobacterium simiae in 26 (47.3%) followed by M.Chelonae in 8 (14.5%), M.Kansasii in 8 (14.5%), M. Abscessus in 6 (10.9%), M.Avium in 5 (9.1%) and M.Farcinogen and M.Genavense each in one case.Cavitary lung lesion was seen in 72.8% and bronchiectasis in 80% of patients.The most predominant symptoms were cough (89.1%), sputum (85, 5%) and dyspnea (65.5%).Fever was present in 22 (40%) of patients.Cure occurred in 38 (69.1%) of patients. Sixteen patients failed treatment and only one patient died.Conclusion: In comparison with other studies M.Simiae was more prevalent and HIV seropositivity was rare.