@article {Melonip3076, author = {Federica Meloni and Carlo Pellegrini and Mirko Belliato and Marinella Zanierato and Alessandro Cascina and Tiberio Oggionni and Andrea D{\textquoteright}Armini and Giorgio Iotti and Antonio Braschi}, title = {Long term outcome of lung recipients bridged with extracorporeal devices}, volume = {38}, number = {Suppl 55}, elocation-id = {p3076}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Recent evolution in extracorporeal supports allows bridging to lung or heart and lung transplant in a consistent number of cases. However, long term results of these transplants have been rarely reported. Aim of present study was to analyse early and long term results in a small n{\textdegree} of lung transplant recipients (LTR) which have been bridged with extracorporeal devices. Nine patients (8 males, mean age39.5) have been transplanted (4SL, 2DL, 3HL). Transplant indications were: UIP (5), PAH (3), bronchiectasis (1). This latter patient (HL) died 3 days after surgery of MOF due to sepsia. 8 patients are alive at a mean of 16 months (min 3.5 - max 33).Early complications included: Re-op for bleeding (1/8) CRYMINE (5/8), slow weaning with need of tracheotomy (7/8), graft infections (1/8), acute renal failure with need for renal replacement therapy in ICU (4/8).Medium long term-complications included: AR\>2 (2/8), CMV pneumonia/reactivation (4/8), Thrombosis (2/8), EBV related haemophagocytic syndrome (1/8); colonization with Ps. aeruginosa or A. fumigatus (2/8) end stage renal failure (RF) (1/8). Two out of 8 patients had an increased in anti HLA class I or II antibody titres (\>10\%).At last follow-up visit graft function was \>90\% of best in 6/8 patient while 2 patients BOS-0p. Mean GFR (MDRD formula) was 54ml/min range between15 and 85.In conclusion: long term survival of ECMO bridged LTR is satisfactory, with good graft function. However, early post transplant period is almost invariably complicated by CRYMINE and slow weaning, and a high degree of chronic RF is detected.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p3076}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }