RT Journal Article
SR Electronic
T1 Combined pulmonary fibrosis and emphysema. Descriptive analysis from a specialized clinic of interstitial lung disease
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p3746
VO 38
IS Suppl 55
A1 M. Asunciόn Nieto
A1 Beatriz Morales
A1 Covadonga Feranadez-Golfín
A1 Paola Benedetti
A1 Gema Rodriguez-Trigo
A1 Ina Gerasimova
A1 José Luis Άlvarez-Sala Walther
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p3746.abstract
AB The combination of pulmonary fibrosis and emphysema (CPFE) is a recently defined syndrome characterized with pulmonary fibrosis (PF) and emphysema.Aim: To analyze the clinical, functional, radiological and echocardiographic features in patients with CPFE.Method: Prospective study conducted in a specialized clinic of ILD from 01/01/2007 to 31/12/2010. PF was defined as reticular opacities with peripheral and basal predominance, honeycombing, architectural distortion and/or traction bronchiectasis without ground glass opacities in HRTC and emphysema as the presence of areas of low attenuation with a very thin or no wall and/or bullaes with upper zone predominance.Results: We anlized 20 patients, 90% men; mean age 74 years; 91% were smokers or ex-smokers, 60% had dyspnoea, 75% basal crackles and 25% finger clubbing. The pulmonary function tests are shown in table 1. Pulmonary hypertension was detected in 5 of 10 patients who underwent echocardiography.View this table:Pulmonary function tests in 20 patientsConclusions: The finding of lung volumes normal o minimally altered in contrast to a severe reduction in TLCO and arterial hypoxemia should alert to the possibility of CPFE. The prevalence of PH in these patients is high.