TY - JOUR T1 - Surgical treatment of primary malignancies of trachea JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p2409 AU - Igor Mosin AU - Nina Mosina AU - Olga Lukina AU - Yana Dorofeeva Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p2409.abstract N2 - The main treatment of patients with primary malignant tumors of the trachea is endoscopic recanalization of the trachea lumen with stenting and radiotherapy. Radical surgery of the trachea primary malignancies is single-step circular resection with end-to-end anastomosis.The aim was to demonstrate that a single-step circular resection is possible when tumor extension is 45% of the trachea length, with involvement of the epiglottis subfold portion.18 single-step circular resections were performed in patients with primary tumor of the trachea. Adenocystic cancer of the trachea was diagnosed in 13 subjects, and typical carcinoid – in 5. Among them over 45% of trachea was resected in 10 patients. Localisation and extension of the tumor was established by fibrobronchoscopy, and MDCT. Tumor extension from 1.0 to 3.0sm was diagnosed in 8 patients, and from 3.0 to 6.0sm – in 10 patients. Single-step circular resections and tracheotracheal anastomosis were performed in 7 patients, laryngotracheal anastomosis - in 6, and a laryngotracheal resections were made in 5 patients. Immediate and prospective results of the treatment are considered to be sufficient in all patients. In Pearson-Grillo laryngotracheal resection the distance between the anastomosis and vocal cords varied from 1 sm to 3 sm.Single-step circular resection is the only radical surgical treatment of primary trachea malignancies. Subfold portion involvement is not a contraindication to a single-step circular resection of the trachea and subfolder portion of the epiglottis. Postoperatively, a single-step circular resection for adenocystic cancer must be followed by radiotherapy. ER -