PT  - JOURNAL ARTICLE
AU  - Andreeva, Yu. A.
AU  - Saidova, M.A.
AU  - Martynyuk, T.V.
AU  - Masenko, V.P.
AU  - Zikov, K.A.
AU  - Volkov, A.V.
AU  - Chazova, I.Ye.
TI  - Right ventricular regional functional changes in patients with pulmonary hypertension of different etiology
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p2319
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p2319.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p2319.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Aim: To evaluate the possibilities of Tissue Doppler Imaging (TDI) in detection of global and regional diastolic dysfunction (DD) of RV in pulmonary hypertension (PH).Materials and methods: 29 pts with idiopathic PH (IPH), 15 with chronic thromboembolic disease (CTD), 18 with systemic scleroderma (SS), 13 with chronic obstructive respiratory disease (CORD), 15 with congenital heart disease (CHD) and 21 in control group (CG) were included in the study. Echo with TDI was operated (Vivid 7, G.E.). NT-proBNP levels were measured (Elecsys 2010, Roche).Results: IPH, CTD and CHD pts had the most increased right and decreased left heart chambers and RV EF accordingly to SPAP, but the highest NTpro-BNP was in CTD. Em from lateral tricuspid ring in IPH was less than in others (p<0,05). But in CTD RV Em from base and apex were comparable with IPH, from middle - the smallest. Em decreased from base to apex in all PH groups.View this table:Table 1. Echo parameters and NT-proBNP levels in PH and controlsConclusion: TDI can be a useful tool for detection early DD in PH. Sensitivity of regional TDI to RV DD was comparable with global.