RT Journal Article SR Electronic T1 Prevalence of airflow obstruction according GOLD, ATS and ERS criteria in symptomatic ever-smokers referring to a pulmonary rehabilitation department JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p3648 VO 38 IS Suppl 55 A1 Elisa De Mattia A1 Adriano Vaghi A1 Ilaria Pessina A1 Giuseppe Pepe A1 Benedetto Rho A1 Nicola Barbarito YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p3648.abstract AB Aim: To evaluate prevalence of airflow obstruction (AO) in ever-smokers ≥ 45 years old with both dyspnoea and chronic productive cough, using European Respiratory society (ERS) statement (FEV1/SVC <88 and <89% predicted in men and women, respectively), American Thoracic Society (ATS) statement (FEV1/FVC <75%), and Global Initiative for Chronic Obstructive Lung Disease (GOLD) statement (FEV1/FVC <70%).Methods: Lung function tests were performed in each patients referred to our Pulmonary Rehabilitation department because of respiratory diagnosis or symptoms. For analysis, in patients showing AO we used post-bronchodilator lung function values.Results: In 184 ever-smoker patients with symptoms of chronic obstructive pulmonary disease (COPD), the prevalence rates of AO were as follows: ERS = 89.7%, ATS = 76.6%, and GOLD = 63.6%. Patients with AO according ERS criteria showing moderate to severe (M/S) obstruction (i.e., FEV1 <70% predicted) were 119. Patients with ERS M/S AO but without AO using either ATS or GOLD criteria were 8.4% and 19.3%, respectively.Conclusions: Prevalence of AO is highly dependent on which guidelines it is based. ATS and particularly GOLD statement can cause a large underdiagnosis even of moderate to severe COPD. Diagnosis of COPD may be overlooked if SVC is not performed.