PT  - JOURNAL ARTICLE
AU  - Eneas Rocco
AU  - Danilo Marcelo Prado
AU  - Alexandre Silva
AU  - Jaqueline Lazzari
AU  - Pedro Bortz
AU  - Debora Rocco
AU  - Amanda Campolin
AU  - Carla Rosa
AU  - Valter Furlan
TI  - Effects of continuous vs. interval aerobic training on PetCO2 response during graded exercise test in patients with coronary artery disease
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p1540
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p1540.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p1540.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Background: Previous studies have demonstrated in patients with coronary artery disease (CAD) that lower values in end-tidal CO2 pressure (PetCO2) during graded exercise test (GET) have been associated with ventilation perfusion (V/Q) mismatch.Purpose: 1) to evaluate the effects of the continuos (CT) and interval aerobic training (IT) on PetCO2 responses during GET in CAD patients; and 2) examine the relationships between PetCO2 at ventilatory anaerobic threshold (PetCO2VAT) and cardiorespiratory parameters after interventions.Methods: 37 patients with CAD (59.7±1.7 years) were divided into 2 groups: CT (n=20; 28.1±1 kg/m2) and IT (n=17; 28.5±1 kg/m2). All patients performed a GET on treadmill to determine VAT and peak oxygen consumption (VO2 peak).Results: CT and IT groups showed increased in relative aerobic fitness (ΔVO2peak = 4.1± 0.4 and 4.4±0.3 ml/kg/min CT and IT, respectively; p<0.05).View this table:PeTCO2 response during graded exercise testSignificant relationships were observed to: 1) CT (PetCO2VAT and VO2peak r=0.49; PetCO2VAT and VEVCO2VAT r= -0.80; P=0.01); and 2) IT (PetCO2VAT and VO2peak r=0.39; PetCO2VAT and VEVCO2VAT r= -0.45; P=0.01).Conclusion: CT and IT demonstrated the same responsiveness in increase PetCO2 values during GET in CAD patients. These results suggest that the factors related to both an increased cardiorespiratory fitness and ventilatory efficiency after interventions may be responsible to increased PetCO2 during GET.