@article {Bourbeaup261, author = {Jean Bourbeau and Denis O{\textquoteright}Donnell and Francois Maltais and Darcy Marciniuk and Andrea Benedetti and Shawn Aaron and Ken Chapman and Robert Cowie and Mark Fitzgerald and Paul Hernandez and Don Sin and Wan Tan}, title = {What are the factors related to misdiagnosis of COPD?}, volume = {38}, number = {Suppl 55}, elocation-id = {p261}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Background: The factors for COPD misdiagnosed by physicians are not known.Objective: To determine the factors associated with COPD misdiagnosed.Methods: This research was part of the Canadian Cohort Obstructive Lung Disease (CanCOLD). Subjects were recruited (population-based sampling) from 9 cities. Physician-diagnosed COPD was based on patient self-reported. COPD was confirmed by spirometry, i.e., post-BD FEV1/FVC \<0.70.Results: This analysis included 2132 subjects from 5 cities. Of 163 with physician-diagnosed COPD, 79 were confirmed to have COPD by spirometry while 84 didn{\textquoteright}t have COPD, 333 had COPD confirmed by spirometry but were undiagnosed, 910 were at risk (ever smoker) and 726 were healthy (never smoker). Among those with physician-diagnosed COPD as compared to undiagnosed COPD, diagnosed subjects were more likely to be current smokers (36\% vs 20\%, p\<0.0001), to have chronic bronchitis (32\% vs 12\%, p\<0.0001), wheezing (64\% vs 38\%, p\<0.0001), dyspnea >=3/5 MRC (22\% vs 9\%, p\<0.0001), diagnosis of asthma (47\% vs 23\%, p\<0.0001), and lower health status. Similar characteristics were present for physician-diagnosed COPD whether or not the diagnosis was confirmed by spirometry. Predictors of physician-diagnosed COPD included current smoking (OR: 1.86, 95\% CI: 1.09-3.18), chronic cough (2.04, 1.13-3.69), chronic bronchitis (2.70, 1.45-5.04), and reduced physical health {\textquotedblleft}SF-12{\textquotedblright} (0.96, 0.96-0.99).Conclusions: Misdiagnosis and underdiagnosis of COPD is common. Current smoking, respiratory symptoms and reduced health seems to trigger physician to make diagnosis of COPD. The absence of these factors may result in underdiagnosis.Funding: CIHR Rx\&D Collaborative Research Program; and the Respiratory Health Network of the FRSQ.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p261}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }