TY - JOUR T1 - Modification of the international primary care airways group (IPAG)-questionnaire for Japanese JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p4219 AU - Go Tsukuya AU - Takuya Samukawa AU - Tsutomu Hamada AU - Kaoru Oketani AU - Masatada Soejima AU - Hiroyuki Nagahama AU - Hirohito Tsubouchi AU - Hiromasa Inoue Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p4219.abstract N2 - Background: Several reports showed the IPAG- Questionnaire (Q) is useful for screening COPD, but may require modification for Japanese. However its modification hasn't been reported yet.Objective: The aim of this study was to establish a modified IPAG-Q for Japanese.Method: Smokers (excepting those with a history of bronchial asthma) aged 40 and over who underwent a screening CT and had given written informed consent were enrolled. They were classified into two groups based on the results of respiratory function tests (FEV1% ≥ or < 70%): control-smokers and a COPD group. We compared the original IPAG-Q between the two groups and statistically analyzed the results to modify it.Results: A total of 268 subjects (control-smokers/COPD: 244/24) were enrolled. We described the receiver operating characteristic (ROC) curve about the original IPAG-Q: the area under the ROC curve (AUC) was 0.764, cut-off was 18.5/total 56 (score), sensitivity was 0.750 and specificity was 0.615. Logistic regression analysis revealed only “wheeze frequency” was useful in the “symptoms/history”, so we deleted “symptoms/history” except for this parameter. And we improved the stratification for age, BMI, and pack/year: age ≥ or < 50 yrs, BMI <18.5/≥ 18.5 & < 25.0/≥ 25.0, and pack/year ≥ or < 30. We then constructed a new scoring system based on the original paper and designed a modified IPAG-Q for Japanese. This modified model was proved valid in the ROC curve; AUC was 0.828, cut-off was 8.5/total 31 (score), sensitivity was 0.833 and specificity was 0.672. This model was superior to the original one.Conclusion: Our modified IPAG-Q is of greater use for screening COPD among Japanese than the original one. ER -