RT Journal Article
SR Electronic
T1 Neurophysiological and functional assessment in patients with difficult asthma control
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p1304
VO 38
IS Suppl 55
A1 Fabiana Canuto
A1 João Corrêa
A1 Luciana Sampaio
A1 Roberto Stirbulov
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p1304.abstract
AB Introduction: Asthma usually responds to treatment with inhaled corticosteroids (with or without the addition of long-acting beta agonists or other drugs) and that means no symptoms and normal lung function or as close to normal as possible. Now, when asthma is inadequately controlled despite a therapeutic strategy adapted and tailored to the level of clinical severity, indicated by a specialist and at least six months duration is regarded Difficult Asthma Control (DAC).Objective: To evaluate the functional and neurophysiological aspects of patients with DAC.Method: We performed a cross-sectional study in three groups of patients: DACC (making use of oral corticosteroids), DACO (which makes use of omalizumab) and GC (healthy controls of similar age). The evaluation was made by testing six-minute walk. Sit-ups test, static balance with the pressure platform, monosynaptics reflexes (patellar and Achilles) and quadriceps strength of the dominant leg.Results: Asthmatic patients have reduced functional capacity, seen testing the six minute walk test and sit-ups (p <0.05), and patients who use oral corticosteroids showed a reduction in the strength of the quadriceps compared to control (p <0.05).