RT Journal Article
SR Electronic
T1 Derivation of a predicted equation for peak expiratory flow (PEF) values in adult Indian population using EU scale peak flow meter (PFM)
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 183
VO 38
IS Suppl 55
A1 Rahul Kodgule
A1 Virendra Singh
A1 Bodigovinda Saicharan
A1 Raja Dhar
A1 Jyoti Londhe
A1 Bill Brashier
A1 Udaiveer Singh
A1 Umar Hafiz
A1 Subhasis Mukherjee
A1 Sapna Madas
A1 Sundeep Salvi
A1 Parvaiz Koul
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/183.abstract
AB Although a PFM is a useful tool for diagnosis and management of asthma, there are no reliable reference values for the adult Indian population. The aim of this study was to derive a predicted equation for PEF for Indian adults using an EU scale PFM.Methodology: 5 centres representing different geographic, ethnic and socioeconomic backgrounds from India were selected (North: Srinagar, West: Jaipur, East: Kolkota, Centre: Pune and South: Hyderabad). Respiratory health and demographic questionnaires were administered to randomly selected 1000 rural and 1000 urban adults from each centre. Sampling was stratified according to gender, height and age. PEF values were measured using Breathometer (Cipla Ltd., India).The predicted equation was generated using linear regression analysis with SPSS software, Version 11.5.Results and conclusion: Out of 9746 participants, 3608 were excluded as unhealthy based on presence of respiratory symptoms, smoking status and/or previous respiratory disease. 80% of the 6138 healthy adults (M: 3720; F: 2418) were used to derive the predicted equation. The equation was validated by comparing the predicted PEF values with the measured values in the remaining 20% sample (Mean ΔPEF: M=3.7 L/min, CI= -0.9,8.3; F=3.1, CI= -1.4,7.6). Gender, age and height were found to be significant determinants of PEF. Using regression analysis, the predicted equations derived in L/min are: F: PEF = 168.551 – 1.776$*$age + 1.354$*$height; M: PEF = 69.259 – 2.290$*$age+ 2.888$*$height. These reference PEF values for Indian adults are 24% lower for males and 27% lower for females than the Caucasian population.