TY - JOUR T1 - Effect of bicarbonate versus acetate hemodialysis on respiratory functions in chronic renal failure patients JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p3616 AU - Mohamed Badawy AU - Ali Taha AU - Nagah Mohamed Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p3616.abstract N2 - Dialysis filter can cause activation of complement and release of anaphylatoxines which can have a deteriorating effect on respiratory system.Aim of the work: To compare the effect of bicarbonate versus acetate haemodialysis on the pulmonary function test and blood gas parameters.Material and methods: Cross sectional study of fifty chronic renal failure patients on regular haemodialysis without history of chronic pulmonary disease were randomly selected for dialysis either by bicarbonate or acetate dialysate twenty five each with same machine and duration of dialysis. Evaluation thorough medical history and determination of forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, and maximal mid-expiratory flow rate (FEF 25%-75%). Arterial oxygen tension (PaO2), PH, carbon dioxide tensions (PaCO2), bicarbonate (HCO3) and potassium were analyzed with a blood gas analyzer.Results: No significant difference in symptoms before and after dialysis in both groups. Improvement of pulmonary function test was significant in bicarbonate group except for FEV1/FVC ratio and PEF. There was significant difference in PaO2, PaCO2 and HCO3 in bicarbonate group.Conclusion: Bicarbonate haemodialysis lead to significant improvement of respiratory functions in chronic renal failure patients on regular dialysis. ER -