RT Journal Article SR Electronic T1 Is quantitative HRCT related with diagnostic yield of fiberoptic bronchoscopy in sarcoidosis? JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p3601 VO 38 IS Suppl 55 A1 Serpil Akten A1 Nurdan Kokturk A1 Gonca Erbas A1 Bulent Celik A1 Haluk Tuktas YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p3601.abstract AB This study aimed to evaluate the diagnostic yield of fiberoptic bronchoscopic (FOB) modalities and its relation with quantitative findings with high resolution computerized tomography (HRCT). 64 patients that consists of 19 males and 45 females with the mean age of 43 diagnosed with sarcoidosis with complete records of HRCT were retrospectively recruited for a time period of Feb 2000 to Jan 2010. HRCT scans were retrospectively assessed in random order by an experienced observer without knowledge of the bronchoscopy result or lung function tests. The diagnostic yield of transbronchial biopsy (TBB) was% 43.6. Although it did not reach statistical significance, the lobar HRCT score in the sampled lobe was associated with a positive TBB result. Bronchial mucosa appearance was significantly related with positive mucosal biopsy (MB). The diagnostic yield of MB was% 24.5 in general patient population however in patients with abnormal mucosa this rate was increased up to% 84.6 (p=0.000). The diagnostic yield of transbronchial needle aspiration (TBNA) was 25.7%. Right hilar and subcarinal lymph nodes were the most diagnostic sites. The diagnostic yield was significantly higher in patients who had larger size of lymph nodes (p=0.007). Quantitavie HRCT score did not correlate with the findings of MB and TBNA.Quantitave HRCT did not cause remarkable impact on the results of diagnostical work up of FOB.