RT Journal Article
SR Electronic
T1 BODE index as a predictor of survival in lung transplantation
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2452
VO 38
IS Suppl 55
A1 Sanjuan, Pilar
A1 Otero, Isabel
A1 Marcos, Pedro J.
A1 Verea, Héctor
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2452.abstract
AB Introduction: Chronic obstructive pulmonary disease (COPD) is one of the most frequent indications for lung transplantation (LTx), but survival benefit is still under debate. We analysed the survival impact of LTx in COPD using the BODE (body mass index, airway obstruction, dyspnoea, exercise capacity) index.Aims: The aim of our study was to analyse the survival impact of lung transplantation in COPD patients. We compared the post-transplant survival with the survival predicted by the BODE index as measured during pre-transplant clinical evaluation.Methods: Retrospective review of 59 consecutive lung transplants performed for COPD in our centre between June 1st 1999 and December 30th 2010. The pre-transplant BODE score was calculated for each patient. Predicted and observed post-transplant survival was then compared.Results: 59 COPD patients were analyzed. Mean age was 57±6 years, 51 (86%) men. 52 (88%) patients had a BODE >7 and 7 (11.9%) <7. The overall survival time was 70.82 months ±8.1, BODE <7 had a overall survival time of 19.5 and BODE > 7 was 73.2±8.6. In the subgroups with a BODE score ≥7 and <7, the 4-year survival was 57% ±0.18 and 57%±0.08 respectively.Conclusions: The results of this study showed a significant survival benefit of LTx in our cohort of COPD patients. Patients with BODE ≥7 will be the ones who benefit the most from the procedure.