RT Journal Article SR Electronic T1 Prognostic importance of congenital stridor occurred during the 1st year of life in children of five years of age JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p1179 VO 38 IS Suppl 55 A1 Elena Striga A1 Olga Zaytseva A1 Yury Soldatsky YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p1179.abstract AB Introduction: Stridor usually manifests after birth or at the age of 1 month and often disappears at 2-4 years of age without any treatment. The absence of data on growth and development of children with congenital stridor in literature have become the point of our research.Objective: To evaluate the impact of congenital stridor in infants as a predictor of chronic diseases.Methods: We examined 114 1-year old patients with congenital stridor. 60 children were included in 5-year catamnesis data. Our cohort consisted of children with persistent congenital stridor, excluding children with stridor due to ARD or tracheal intubation.Results: On their admission to the hospital all children had stridor of various degrees, 21,9% had regurgitation, 7% - choking, 7,9% - projectile vomiting, 5,3% were short-winded, 4,4% had sleep apnea and voice change. All children underwent thorough examination, rhinolahryngoscopy was performed in 94 patients.Laryngomalacia was diagnosed in 80%, accompanied by pharyngolaryngeal reflux and gastroesophageal reflux in 93,3%. Reflux-esophagitis without inflammatory changes was found in 53,3%. All patients had connective tissue dysplasia. Mitral valve failure was present in 35%, PFO - in 16,7%, heart rate abnormalities - in 21,7%. Chest deformations were found in 45%, hypermobility of joints - in 38,8%.Conclusions: Congenital stridor may serve as a predictor of chronic disorders of gastrointestinal tract, ENT-system, dysplasia of connective tissue, cardiovascular diseases. Children with congenital stridor need to undergo detailed examinations and long-term regular medical check-ups in order to minimize the risk of complications.