RT Journal Article
SR Electronic
T1 Rare localization of extra pulmonary tuberculosis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2690
VO 38
IS Suppl 55
A1 Jihen Ben Amar
A1 Besma Ourari
A1 Leila El Gharbi
A1 Saloua Azzabi
A1 Mohamed Ali Baccar
A1 Hichem Aouina
A1 Hend Bouacha
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2690.abstract
AB Tuberculosis (TB) can involve any organ system in the body by way of hematogenous or lymphatic dissemination or contiguity. While pulmonary tuberculosis is the most common presentation, extrapulmonary tuberculosis (EPTB) is also an important clinical problem.The aim of the present study is to describe clinical manifestations and the outcome of patients with EPTB.Materials and methods: We report the cases of 30 patients (17 men and 13 women) with a mean age 44 years (17-80 years) hospitalized for EPTB from January 2000 to January 2011.Results: Seven patients (23%) had fever, loss of weight, anorexia ant sweating; pain in effected site was noted in 6 cases (20%).Urinary (16%), female genital (16%) and splenic tuberculosis (16%) were the most common site of involvement followed by parietal abscess (13.5%), abdominal (13.5%) and laryngeal tuberculosis (6%). The other localizations, spinal, skin, meningitis, haematopoietic, hepatic, tongue and thyroid gland were noted in only in one case (3%). Miliary tuberculosis was found in 3 cases (10%). Pulmonary tuberculosis was associated in 53%.Tuberculosis was microbiologically proven in only 33% of cases. The diagnostic was confirmed by a tissue samples in 12 patients (40%).Mean course of standard anti-TB therapy (isoniazid, rifampin, pyrazinamide, streptomycin or ethambutol) was 8,5 months, cure was noted in 83,% and lost to follow-up in 17%.Conclusion: High index of clinical suspicion, the use of invasive diagnostic methods for the confirmation of the diagnosis, early institution of specific antituberculosis treatment are the key to the successful management of EPTB.