RT Journal Article SR Electronic T1 Effect of hyperoxygenation on measurement of the maximum inspiratory pressure (MIP) in critical patients JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p1287 VO 38 IS Suppl 55 A1 Araújo, Indianara A1 Vieira, Vanessa A1 Valois, Marco A1 Albuquerque, Claudio A1 Ferrari, Francimar YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p1287.abstract AB The assessment of the maximum inspiratory pressure (MIP) is used as an indicator of inspiratory muscle strength and may be useful in evaluating the success of weaning from mechanical ventilation. During this procedure it is common that a fall of saturation peripheral O2 (SpO2) occurs, leading to discontinuation of the maneuver, which can underestimate the value of MIP.The objective of this study is to verify whether the implementation of hyperoxygenation prior to the assessment can mitigate this decline of SpO2, increasing the measurement support time (to) and generating a more reliable MIP.The evaluation of the MIP, occlusion time (OT), SpO2, respiratory rate (RR) and heart rate (HR) was carried out randomly on 26 patients, with or without hyperoxygenation prior, maintaining the duration of occlusion of unidirectional valve for an indefinite period. Hyperoxigenation was defined as the use of inspired oxygen fraction (FiO2) to 100%, two minutes before the maneuver. The measurement was performed with the patient in the supine position and elevated head with an angle of 60 °.The value of MIP and OT were higher with previous hyperoxygenation (53.77±22.37 cmH2O vs 43.38±20.11 cmH2O/p<0.001; and 58.69±26.09 sec vs 37.04±15.07 sec/p< 0.001; respectively). In addition, there was a smaller drop in SpO2 after the measurement when the method was performed with hyperoxygenation (93.15±7.24% vs 84.58±9.73%/p<0.001). There was increase in RR and HR independently of the hiperoxynation.Implementation of hyperoxygenation prior to the assessment of MIP increase the values obtained, generating a more reliable MIP.