TY - JOUR T1 - Idiopathic pulmonary arterial hypertension in the elderly: Data from the French registry JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p1528 AU - Frédéric Lador AU - Olivier Sitbon AU - Azzedine Yaïci AU - Emmanuel Bergot AU - Vincent Cottin AU - Laurence Rottat AU - Virginie Gressin AU - Marc Humbert AU - Gérald Simonneau Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p1528.abstract N2 - Rationale: Data from recent registries have shown that the mean age of patients with pulmonary arterial hypertension (PAH) is increasing.Aim: To describe clinical and haemodynamic characteristics of incident (i.e. newly diagnosed) patients >70 yr included in the French Registry with a diagnosis of idiopathic (IPAH), heritable (HPAH) or anorexigen-related (ArPAH) PAH.Methods: Data from all newly-diagnosed adult patients with IPAH, HPAH or ArPAH included in the French Registry between November 2006 and November 2009 were collected. Patients without right heart catheterization confirmation and those with a pulmonary capillary wedge pressure > 15 mmHg were excluded.Results: Among the 350 patients who met the inclusion criteria, 100 (28.5%) were >70 yr. Clinical and haemodynamic characteristics at time of diagnosis are shown in the Table. Survival rates at 1, 2 and 3 years were 79%, 60% and 47% in those >70 yr, as compared to 92%, 84% and 76% in the 18-70 yr group, respectively (p<0.01).View this table:Conclusions: These results show an increasing proportion of elderly male among patients with IPAH and ArPAH. Patients >70 yr have a worse outcome than younger patients despite a less severe haemodynamic impairment. ER -