TY - JOUR T1 - Metabolic syndrome and incidence of asthma in adults: the HUNT study JF - European Respiratory Journal JO - Eur Respir J SP - 1495 LP - 1502 DO - 10.1183/09031936.00046013 VL - 42 IS - 6 AU - Ben Michael Brumpton AU - Carlos Arturo Camargo, Jr AU - Pål Richard Romundstad AU - Arnulf Langhammer AU - Yue Chen AU - Xiao-Mei Mai Y1 - 2013/12/01 UR - http://erj.ersjournals.com/content/42/6/1495.abstract N2 - Obesity is a risk factor for incident asthma in adults, and obesity is a major component of metabolic syndrome. This study aimed to explore the associations of metabolic syndrome and its components with the cumulative incidence of asthma in adults. We conducted a prospective cohort study of participants who were asthma-free at baseline (n = 23 191) in the Nord-Trøndelag Health Study from 1995 to 2008. Baseline metabolic syndrome was categorised using the definition of the Joint Interim Statement from several international organisations. Incident asthma was self-reported at follow-up, which averaged 11 years. Metabolic syndrome was a risk factor for incident asthma (adjusted OR 1.57, 95% CI 1.31–1.87). This association was consistent in sensitivity analyses using a stricter asthma definition (adjusted OR 1.42, 95% CI 1.13–1.79). Among the components of metabolic syndrome, two remained associated with incident asthma after mutual adjustment for the other metabolic components: high waist circumference (adjusted OR 1.62, 95% CI 1.36–1.94) and elevated glucose or diabetes (adjusted OR 1.43, 95% CI 1.01–2.04). Metabolic syndrome and two of its components (high waist circumference and elevated glucose or diabetes) were associated with an increased risk of incident asthma in adults. Metabolic syndrome and two of its components were associated with an increased risk of incident asthma in adults http://ow.ly//p2RNy ER -