RT Journal Article
SR Electronic
T1 The impact of COPD on health status: findings from the BOLD study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1472
OP 1483
DO 10.1183/09031936.00153712
VO 42
IS 6
A1 Christer Janson
A1 Guy Marks
A1 Sonia Buist
A1 Louisa Gnatiuc
A1 Thorarinn Gislason
A1 Mary Ann McBurnie
A1 Rune Nielsen
A1 Michael Studnicka
A1 Brett Toelle
A1 Bryndis Benediktsdottir
A1 Peter Burney
YR 2013
UL http://erj.ersjournals.com/content/42/6/1472.abstract
AB The aim of this study was to describe the impact of chronic obstructive pulmonary disease (COPD) on health status in the Burden of Obstructive Lung Disease (BOLD) populations.We conducted a cross-sectional, general population-based survey in 11 985 subjects from 17 countries. We measured spirometric lung function and assessed health status using the Short Form 12 questionnaire. The physical and mental health component scores were calculated.Subjects with COPD (post-bronchodilator forced expiratory volume in 1 s/forced vital capacity <0.70, n = 2269) had lower physical component scores (44±10 versus 48±10 units, p<0.0001) and mental health component scores (51±10 versus 52±10 units, p = 0.005) than subjects without COPD. The effect of reported heart disease, hypertension and diabetes on physical health component scores (-3 to -4 units) was considerably less than the effect of COPD Global Initiative for Chronic Obstructive Lung Disease grade 3 (-8 units) or 4 (-11 units). Dyspnoea was the most important determinant of a low physical and mental health component scores. In addition, lower forced expiratory volume in 1 s, chronic cough, chronic phlegm and the presence of comorbidities were all associated with a lower physical health component score.COPD is associated with poorer health status but the effect is stronger on the physical than the mental aspects of health status. Severe COPD has a greater negative impact on health status than self-reported cardiovascular disease and diabetes.COPD is related to worse health status: impairment is greater than in self-reported cardiovascular diseases or diabetes http://ow.ly/p1cIx